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ML133 HCl

CAS No. 1222781-70-5

ML133 HCl ( —— )

Catalog No. M17888 CAS No. 1222781-70-5

ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ML133 HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
  • Description
    ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    Kir2.1
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    1222781-70-5
  • Formula Weight
    313.82
  • Molecular Formula
    C19H19NO·HCl
  • Purity
    98%
  • Solubility
    DMSO : ≥ 125 mg/mL; 398.32 mM
  • SMILES
    Cl.COC1=CC=C(CNCC2=CC=CC3=C2C=CC=C3)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang HR, et al. ACS Chem Biol, 2011, 6(8), 845-856.
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